Tuesday, February 5, 2013

Why Is Arthritis Common Among Obese?


 Overweight people is prone of getting health problems like developing arthritis, a medical expert says. What usually triggers a person to undergo the divisive hip replacement from DePuy Orthopeadics, a unit of Johnson & Johnson, is the development of Arthritis which is about 10,100 lawsuits were being filed even after it made a recall in 2010. Arthritis has numerous type which has over 100 medical conditions. The Osteoarthritis (OA) is considered as the most frequently complained type of arthritis and usually have an effect on ageing patients. There are various forms of arthritis which may have an effect on people at a very untimely age, the Medical News Today website reports.



Being overweight or obese is one of the most significant and potentially a risk factors in the development of osteoarthritis. There are various researches which revealed a strong connection between body mass index and osteoarthritis of the hip, knee, foot and hand.

However, the mechanism(s) by which obesity contributes to the onset and progression of osteoarthritis are not fully understood.

The strong linked between body mass index, altered limb alignment, and osteoarthritis of the knee –and the defensive effects of weight loss — hold up the classic hypothesis that the effects of obesity on the joint are due to increased bio-mechanical loading and associated alterations in gait.

However, obesity is now considered to be a low-grade systemic inflammatory disease. Current researches advise that metabolic factors associated with obesity alter systemic levels of pro-inflammatory cytokines that are also associated with osteoarthritis.

Thus, the final pressure of obesity on osteoarthritis may absorb a complex interaction of genetic, metabolic, and bio-mechanical factors. In this respect, mouse models of obesity can provide excellent systems in which to examine causal relationships among these factors. In recent years, there have been surprisingly few reports examining the effects of obesity on osteoarthritis using mouse models.

It is always best to be mindful of becoming fit and healthy which may help a person prevent a chronic disease such as arthritis, of which the excruciating pain may lead to surgery such as hip replacement and about which remains the subject of several hip replacement. For more related information, please click here.